Study on the effect of anticholinergic drug exposure on the occurrence of Alzheimer's disease and establishment of drug risk warning model

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2000037273

Enrollment

Unknown

Registered

2020-08-27

Start date

2020-10-01

Completion date

Unknown

Last updated

2020-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Alzheimer's disease

Interventions

case series:Nil

Eligibility

Sex/Gender

All

Age

60 Years to 100 Years

Inclusion criteria

Inclusion criteria: Jing'an Temple community is located in the southwestern part of Shanghai City, China. According to the annual census at the end of 2009, the target population lived in 11 communities, with 5138 registered residents over 60 years old. Eligible research subjects are: (1) Registered residents of the community; (2) >= 60 years; or (3) Able to communicate and receive physical and cognitive examinations . This study was approved by the Medical Ethics Committee of Huashan Hospital of Fudan University. Have obtained written informed consent from all participants and/or their legal representatives.

Exclusion criteria

Exclusion criteria: People with schizophrenia or mental retardation based on medical records.

Design outcomes

Primary

Measure	Time frame
Types and intensity of anticholinergic drugs;Aß40, Aß42 and Tau;	—

Secondary

Measure	Time frame
Total anticholinergic exposure burden;	—

Countries

China

Contacts

Public ContactChi Danyi

Huashan Hospital, Fudan University

702197768@qq.com+86 13818144610

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026