postherpetic neuralgia
Conditions
Interventions
control group:Intervention with valacyclovir for 1 week
experimental group:Intervention with valacyclovir for 2 weeks
Sponsors
Shanghai Dermatology Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Meet the diagnostic criteria for herpes zoster and meet the age criteria for middle-aged and elderly people:? (1) Aged >= 50 to 79 years; (2) The course of disease is less than one week; ?? (3) Patients without antiviral and analgesic treatment; ?? (4) Those who voluntarily sign an informed consent form and are willing to actively cooperate with treatment.
Exclusion criteria
Exclusion criteria: (1) People with special types of herpes zoster; ?? (2) Combined with life-threatening primary diseases such as cardiovascular, cerebrovascular, liver, lung, kidney, hematopoietic system, and other endocrine system diseases or systemic diseases that manifest as fibromyalgia, such as osteoporosis, severe trauma, and malignancy Tumors, etc.; (3) Female patients during pregnancy or lactation; (4) People with allergies or physical weakness and intolerance.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Comprehensive efficacy evaluation;Blistering time;Scab time;Sensory nerve quantification;Visual analog scale;Viral nucleic acid quantitative PCR detection;Dermatology Life Quality Index, DLQI;Safety evaluation; | — |
Countries
China
Contacts
Public ContactWencheng Jiang
Shanghai Dermatology Hospital
Outcome results
None listed