Lumbar osteoporotic vertebral compression fractures
Conditions
Interventions
Group NICE :NICE operation
Group PVP:PVP operation
Sponsors
Shanghai Changzheng Hospital
Eligibility
Sex/Gender
All
Age
45 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1) The age of the patients was 45-75 years old, and they were willing to sign the informed consent; 2) The patient was diagnosed as osteoporotic vertebral compression fracture; 3) The patients presented with lumbar pain, activity limitation, numbness and weakness of lower limbs, nerve root compression symptoms, which may be accompanied by dysfunctions of urination and defecation.
Exclusion criteria
Exclusion criteria: 1) Inflammatory diseases such as lumbar tumor, lumbar disc herniation, degenerative scoliosis, lumbar tuberculosis, etc; 2) Patients with other spinal diseases affecting clinical symptoms; 3) Other diseases such as amyotrophy of the motor cord and other diseases were found; 4) Poor physical condition, unable to tolerate surgery; 5) The patients (or their guardians) with cognitive dysfunction can not give full informed consent; 6) Patients who participated in other clinical trials in the past month; 7) Patients with active hepatitis B (including large three positive or small three positive) or serological markers (HBsAg or / and HBeAg or / and HBcAb), hepatitis C, pulmonary tuberculosis, cytomegalovirus, severe fungal infection or HIV infection; 8) There were active peptic ulcer in 3 months before randomization.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VAS score; | — |
Secondary
| Measure | Time frame |
|---|---|
| SF-36; | — |
Countries
China
Contacts
Public ContactWang Yuan
Shanghai Changzheng Hospital
Outcome results
None listed