elderly patients undergoing laparoscopic cholecystectomy
Conditions
Interventions
standard PEEP:standard PEEP
Driving pressure target-controlled PEEP:Driving pressure target-controlled PEEP
Sponsors
Meirong Yang
Eligibility
Sex/Gender
All
Age
65 Years to 80 Years
Inclusion criteria
Inclusion criteria: Patients were approached by study staff and were eligible if they: (1) are aged from 65 to 80 years old; (2) had an American Society of Anesthesiology Physical Status score of I~II grade; and (3) 18kg/m2 <= BMI <= 30kg/m2; (4) planned for laparoscopic cholecystectomy.
Exclusion criteria
Exclusion criteria: (1) those who refused to participate in the experiment and did not sign the informed consent form; (2) the patients had symptoms of upper respiratory tract infection or pulmonary infection in the past 4 weeks. Or Chest X-ray showed pneumonia; (3) diseases affecting thoracic and pulmonary compliance, such as chicken chest, funnel chest, chest trauma and surgery, chronic obstructive emphysema, pleural effusion and acute respiratory distress syndrome; (4) history of neuromuscular dysfunction; (5) serious cardiovascular events, lung, kidney and hematopoietic system diseases; (6) patients who had received general anesthesia in the first 7 days at random; (7) patients with mental system diseases and cognitive impairment, and patients with previous history of psychotropic and narcotic substance abuse; (8) other conditions in which the researchers determined that the patient was not suitable to participate in the clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Respiratory mechanics index;Blood gas and oxygenation index; | — |
Countries
China
Contacts
Public ContactMeirong Yang
Shanghai General Hospital
Outcome results
None listed