Chronic hepatitis
Conditions
Interventions
CHB 
damp-heat 
Gold Standard:TCM syndrome diagnosis relies on experience and the guidance of TCM theory in clinical practice, which is subjective.
and 
verify 
the 
markers 
be 
used 
for 
diagnosis 
of 
Sponsors
Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Meet the criteria for diagnosis of chronic hepatitis B or non-alcoholic fatty liver disease and TCM syndrome diagnosis; Aged 18-65 years; Sign informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with other liver diseases such as other hepatotropic virus infection, alcoholic fatty liver, autoimmune diseases, chronic hepatitis B and non-alcoholic fatty liver disease; 2. Patients with chronic severe hepatitis and liver cirrhosis; 3. Accompanied by severe primary disease of heart, kidney, lung, endocrine, blood, metabolism and gastrointestinal tract; 4. Mentally ill; 5. Pregnant or breastfeeding women; 6. Those who have performed gastrointestinal bariatric surgery within the past year or those who have taken weight-loss drugs; within the past 3 months have lost > 10% of their weight.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Peripheral blood transcriptomics;Metabolomics; | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood lipids, fasting blood glucose, AFP, HBV-DNA, hepatitis B markers, HbA1c, fasting insulin;MRI-PDFF;TCM Syndrome Scale; | — |
Countries
China
Contacts
Public ContactYiyang Hu
Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine
Outcome results
None listed