High myopia in children
Conditions
Interventions
control group:0.01%atropine
Intervention group:Low energy laser therapy+0.01%atropine
Sponsors
Shanghai Eye Disease Prevention and Treatment Center
Eligibility
Sex/Gender
All
Age
6 Years to 12 Years
Inclusion criteria
Inclusion criteria: 1. Age ranged from 6 to 12 years. Sex is not limited; 2. Diagnosis of myopic ametropia in any eye; after mydriasis, the myopia spherical lens is more than 4.00D, astigmatism < 2.00D, anisometropia < 3.00D; the best corrected visual acuity was at least 0.8, and the near visual acuity was at least 1.0; 3. Having normal thinking and language communication skills, being able to cooperate with the treatment actively; 4. No contraindications of atropine therapy. No acute ocular inflammation, dry eye, keratoconus, and diabetes; 5. Informed consent signed by guardians and children.
Exclusion criteria
Exclusion criteria: 1. History of photoallergy, glaucoma, glaucomatocyclitis, ocular hypertension, macular lesions or injuries 2. High myopiawith leopard like changes in fundus retina; 3. Combined with heart, liver, kidney and other systemic diseases and congenital hereditary myopia; 4. Combined with ocular injuries, strabismusoperated eyes, allergic conjunctivitis and other chronic eye diseases; 5. Pre-existing entropion, trichiasis, serious keratoconjunctival infection and other eye diseases; 6. Patients with nervous system diseases and allergy or contraindications to atropine or other therapeutic drugs; 7. Patients with immune system and systemic diseases such as albinism, psoriasis, nephrotic syndrome, systemic lupus erythematosus, diabetes, etc; 8. Epilepsy, mental disorders, unable to communicate normally; 9. Having received other treatments to control the development of myopia; 10. Other situations that are judged by the researcher to be unsuitable to participate in the research.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| myopic refraction; | — |
Countries
China
Contacts
Public ContactYan Yu
Shanghai Eye Disease Prevention and Treatment Center
Outcome results
None listed