idiopathic epiretinal membrane
Conditions
Interventions
Group 1:micropulse laser therapy combined with oral drugs
Group 2:only oral drugs
Sponsors
Joint Shantou International Eye Center of Shantou University and the Chinese University of Hong Kong
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1) Aged 18 to 75 years old; 2) Dianosed with idiopathic epiretinal membrane with the best correted visual acuity of less than 10/20 or metamorphopsia, and with central foveal thickness of over 250 um using optical coherence tomography; 3) Had no history of surgery or laser therapy; 4) prepared for PPV surgery combined with inner limiting membrane peeling and intravitreal injectional of triamcinolone acetonide at a dose of 2mg/0.05ml; 5) Patients are voluntarily involved in this clinical trial and signed informed consent
Exclusion criteria
Exclusion criteria: 1) combined with other vision-threatening eye diseases including vitreal hemorrhage, glaucoma, diabetic retinopathy, and other retinal neovascular diseases; 2) suffer from ocular complications after surgery, such as high intraocular pressure, retinal hemorrhage, infection, etc; 3) combined with uncontrolled systemic disorders, such as hypertension,cardiovascular and cerebrovascular diseases, severe cardiac dysfunction, etc; 4) Showed difficulties in cooperating with the operators or poor OCT/OCTA image quality.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| best corrected visual acuity;central retinal thickness;superficial capillary plexus, SCP;deep capillary plexus, DCP;foveal avascular zone, FAZ; | — |
Secondary
| Measure | Time frame |
|---|---|
| retinal microstructure; | — |
Countries
China
Contacts
Public ContactHongjie Lin
Joint Shantou International Eye Center of Shantou University and the Chinese University of Hong Kong
Outcome results
None listed