Thoracoscopic lobectomy
Conditions
Interventions
Sponsors
Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1) The ASA grade was I - III; 2) Aged 18-65 years, no gender limit; 3) Patients without previous immune system diseases; 4) Sign informed consent.
Exclusion criteria
Exclusion criteria: Study one exclusion criteria 1) Patients who have participated in other clinical trials in the past four weeks; 2) Patients who could not cooperate to complete the study included infectious diseases and other medical history; 3) Patients with positive urine pregnancy test; 4) Patients with preoperative pain, using central analgesics, opioid addicts and addicts; 5) Severe other system diseases and serious mental diseases were found before operation; 6) Patients with abnormal liver and kidney function (ALT, AST, BUN, Cr exceeding 1.5 times of normal value); 7) BMI>=30kg/m2 or Weight less than 50kg; 8) Organic heart disease or arrhythmia; 9) Emergency surgery or video-assisted thoracoscopic surgery; 10) Spinal deformity, abnormal blood coagulation, and infection of puncture site of erector spinalis plane block. Study 2 exclusion criteria 1) Patients with skin infection at acupoints and limb nerve injury; 2) Patients who have participated in other clinical trials in the past four weeks; 3) Patients who could not cooperate to complete the study included infectious diseases and other medical history; 4) Patients with positive urine pregnancy test; 5) Patients with preoperative pain, using central analgesics, opioid addicts and addicts; 6) Severe other system diseases and serious mental diseases were found before operation; 7) Patients with abnormal liver and kidney function (ALT, AST, BUN, Cr exceeding 1.5 times of normal value); 8) BMI>=30kg/m2 or Weight less than 50kg; 9) Organic heart disease or arrhythmia; 10) Emergency surgery or video-assisted thoracoscopic surgery; 11) Spinal deformity, abnormal blood coagulation, and infection of puncture site of erector spinalis plane block.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes of vital signs at the beginning of skin incision;Does the patient have agitation when extubation tracheal tube;Whether or not to use remedial analgesics 2 hours after operation and VAS score;Intraoperative remifentanil dosage; | — |
Secondary
| Measure | Time frame |
|---|---|
| Intraoperative remifentanil dosage;Time of spontaneous respiration recovery after anesthesia induction;The highest value of partial pressure of carbon dioxide in blood gas analysis during operation;The changes of blood indexes such as plasma cortisol, pain mediators ß - endorphin, 5-hydroxytryptamine, inflammatory mediators IL-6 and TNF - a before and after operation; | — |
Countries
China
Contacts
Public ContactHaifeng Shi
Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Medicine
Outcome results
None listed