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Cumulative live birth rate and offspring evaluation for mosaic X chromosome aneuploidy female after IVF/ICSI treatment, a prospective cohort study

Cumulative live birth rate and offspring evaluation for mosaic X chromosome aneuploidy female after IVF/ICSI treatment, a prospective cohort study

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000037218
Enrollment
Unknown
Registered
2020-08-27
Start date
2020-08-24
Completion date
Unknown
Last updated
2020-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

mosaic X chromosome aneuploidy female

Interventions

mosaic X chromosome aneuploidy female vs. normal group:Nil

Sponsors

Shanghai First Maternity and Infant Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: Case group: Mosaic X chromosome aneuploidy female (mosaism with at least 2 kinds of 45,X/47,XXX/48,XXXX/46,XX) and male partner with 46,XY, who will take IVF/ICSI in our center.

Exclusion criteria

Exclusion criteria: Couples with any other chromosome abnormalitis,or going to take preimplantation genetic diagnosis/donated gametes,or with infecous diseases(HIV/HBV/HCV/Syphilis positive), or with other health problems not suitable to reproduce, or not suitable to take ART, or imposible to follow-up.

Design outcomes

Primary

MeasureTime frame
live birth;

Secondary

MeasureTime frame
total gonadotrophin;days of Gn;oocyte number;usable embryo number;clinical pregnancy rate;birth defect;

Countries

China

Contacts

Public ContactShanshan Liang

Shanghai First Maternity and Infant Hospital

000ella@163.com+86 13564814880

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026