Parkinson's disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Diagnosed as idiopathic Parkinson's disease according to Diagnostic criteria of Parkinson's disease; (2) Age between 50-70 years; (3) Hoen and Yahr 1-3; (4) The drug dose was stable 2 months before participating in the trial; (5) Can walk for 6 minutes without support and crutches and able to stand and sit; (6) MMSE>24, can understand and coordinate the treatment; (7) Able to read and sign informed consent.
Exclusion criteria
Exclusion criteria: (1) Combined with other mental diseases; (2) Patients with epilepsy and those taking drugs that can cause epilepsy; (3) Combined with other organic intracranial diseases, such as Alzheimer's disease, autoimmune encephalitis, vascular dementia, acute massive cerebral infarction and so on; (4) Combined with severe systemic disease, such as heart disease, hypertension, nephrosis and so on; (5) Experience fractures within six months. Have osteopathy or arthropathy which can influence gait; (6) Use implanted electronic devicessuch as cardiac pacemaker and deep brain stimulator; (7) Have a history of brain surgery; (8) Use implanted metallic materials, such as skull restore materials and vascular stent; (9) Combined with intracranial hypertension and headache; (10) Hemorrhagic tendency; (11) Combined with acute infectious diseases, fever, electrolyte disturbance and unstable vital signs; (12) Combined with neoplastic disease; (13) Skin injury, skin inflammation or hyperalgesia in the areas which are stimulated; (14) Is participating in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Unified-Parkinson Disease Rating Scale III;Berg Balance Scale;Five Times Sit to Stand;10 Minutes Walking Test;Timed Up and Go Test;Simple Test for Evaluating Hand Function;Mini-Mental State Examination;Stroop color-word test; | — |
Countries
China
Contacts
Huashan Hospital, Fudan University