post-trauma severe elbow stiffness
Conditions
Interventions
Group 1:Intra-Articular Tranexamic Acid 1g
Group 2:Intravenous Tranexamic Acid 1g
Group 3:Intravenous 1g and Intra-Articular Tranexamic Acid 1g plus
Sponsors
Shanghai Jiao Tong University Affiliated Sixth People's Hospital
Eligibility
Sex/Gender
Male
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1) no regaining a functional arc of motion from 6 months of nonoperative treatment; (2) severe elbow stiffness (defined as ROM <= 60 degrees according to the classification proposed by Mansat and Morrey.
Exclusion criteria
Exclusion criteria: (1) known allergy to TXA; (2) preoperative hemoglobin of less than 100 g/L; (3) known bleeding disorders; (4) concomitant severe comorbidities (renal failure, serious pulmonary disease, myocardial infarction, coronary disease, myocardial infarction, previous thrombosis); (5) associated with nonunion or malunion of elbow; (6) associated with burns or central nervous system trauma; (7) previous operation history of internal fixation or open release in the affected elbow side.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Inflammatory index; | — |
Secondary
| Measure | Time frame |
|---|---|
| ?brinolysis index;Swelling of elbow joint;Pain at rest;pain on motion;Analgesic dosage; | — |
Countries
China
Contacts
Public ContactCunyi Fan
Shanghai Jiao Tong University Affiliated Sixth People's Hospital
Outcome results
None listed