Clinical translational study of supercooling-based preservation technology to extend the preservation time and improve preservation quality of donor liver

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000037195

Enrollment

Unknown

Registered

2020-08-27

Start date

2020-10-01

Completion date

Unknown

Last updated

2020-10-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Liver transplantation

Interventions

Supercooling group:Supercooling preservation

Control group:UW preservation

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. End-stage liver disease; 2. The donor liver comes from brain-dead organ donations from Chinese citizens; 3. The age of the donor is between 18-60 years old, and the age of the recipient is between 18-70 years old; 4. Sign the Consent; 5. Tumors of patients with liver cancer must meet the Hangzhou criteria; 6. Receipt MELD score < 30 points.

Exclusion criteria

Exclusion criteria: 1. Retransplantation; 2. Receipt with fulminant liver failure; 3. HIV positive; 4. With serious systemic infection; 5. Multiple organ transplantation.

Design outcomes

Primary

Measure	Time frame
Liver function;	—

Secondary

Measure	Time frame
Liver vascular function;Serum cytokines;Coagulation function;Renal function;Pathological score;Apoptosis score;Liver ultrastructure;Immune cell infiltration;Complication rate;One-year survival;Three-year survival;	—

Countries

China

Contacts

Public ContactLin Zhong

Shanghai General Hospital

zhonglin1@medmail.com.cn+86 13917603139

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026