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Professor Xu Minhua JieYuPing square curative effect on senile hypertension combined anxiety state observation on Ang II impact study

Professor Xu Minhua JieYuPing square curative effect on senile hypertension combined anxiety state observation on Ang II impact study

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000037162
Enrollment
Unknown
Registered
2020-08-27
Start date
2021-01-01
Completion date
Unknown
Last updated
2020-10-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hypertension

Interventions

Sponsors

Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. It conforms to the western medicine diagnosis of hypertension in the elderly and the diagnostic criteria of TCM syndromes of Yin deficiency and Yang hyperactivity; 2. Age <= 65 years old and <= 85 years old, regardless of gender; 3. The anxiety self-rating Scale (SAS) was assessed as mild or moderate anxiety (50-69 points); 4. Hamilton Anxiety Scale (HAMA) was assessed as likely to have anxiety, definitely to have anxiety or definitely to have obvious anxiety (scoring 7 ~ 28 points); 5. Did not use anti-anxiety and depression drugs 2 weeks before enrollment; 6. Understand and agree to participate in this study and sign the informed consent (if necessary, give the informed consent to the legal guardian and ask him to sign the informed consent).

Exclusion criteria

Exclusion criteria: 1. Secondary hypertension and malignant hypertension; 2. Anxiety disorders caused by thyroid disease, cervical spondylosis and other diseases; 3. Patients with severe liver and kidney dysfunction, high atrioventricular block, acute heart failure, myocardial infarction, acute cerebral infarction, cerebral hemorrhage, diabetic ketoacidosis and malignant tumor; 4. Those with language and cognitive impairment who fail to cooperate and are diagnosed with Alzheimer's disease (AD) vascular dementia (VD); 5. Allergic to amlodipine besylate tablets and Traditional Chinese medicine.

Design outcomes

Primary

MeasureTime frame
Clinical blood pressure;SAS;HAMA;TCM syndrome score;Angiotensin II;

Secondary

MeasureTime frame
Daily blood pressure;Quality of Life evaluation;

Countries

China

Contacts

Public ContactGu Juan

Yueyang Hospital of Integrated Traditional Chinese and Western Medicine,Shanghai University of Traditional Chinese Medicine

gujuan_2012@126.com+86 13301755613

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026