Effect of DDR gene mutation on the efficacy of immunotherapy for cervical cancer

Effect of DNA Damage Repair gene mutation on the efficacy of immunotherapy for cervical cancer

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000037138

Enrollment

Unknown

Registered

2020-08-27

Start date

2020-10-01

Completion date

Unknown

Last updated

2020-10-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cervical Cancer

Interventions

experimental group:Immunotherapeutic drugs

Eligibility

Sex/Gender

Female

Age

20 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) Histologically confirmed advanced unresectable and / or metastatic cervical cancer (squamous cell carcinoma, adenocarcinoma, adenosquamous cell carcinoma), and disease progression occurred during or after previous platinum-containing chemotherapy; (2) staining confirmed that the tumor cell content was more than 20%.

Exclusion criteria

Exclusion criteria: Patients with cervical cancer who are not suitable for immunotherapy in this study.

Design outcomes

Primary

Measure	Time frame
OS;	—

Countries

China

Contacts

Public ContactShengyun Cai

Shanghai Changhai Hospital

caicai24@126.com+86 13916466362

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026