EEG-based repetitive transcranial magnetic stimulation over dorsolateral DLPFC in methamphetamine use disorder: a randomized multi-center double-blinded clinical trial

Individualized responding frequency based repetitive transcranial magnetic stimulation (r-TMS) over dorsolateral prefrontal cortex (DLPFC) for methamphetamine addiction: a randomized multi-center double-blinded clinical trial

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000037136

Enrollment

Unknown

Registered

2020-08-27

Start date

2020-10-01

Completion date

Unknown

Last updated

2020-10-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

methamphetamine use disorder

Interventions

intervention group:rTMS over left DLPFC

sham group:sham rTMS

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: (1) Meet DSM-5 criteria for substance abuse; (2) Aged 18-60 years; (3) Junior high school degree or above; (4) Consent to attend this study; (5) The drug abuse time is more than one year, the frequency of use is greater than one week, and the monthly use is greater than 1 gram.

Exclusion criteria

Exclusion criteria: (1) Have contraindications to TMS (head trauma, epilepsy or the history of epilepsy, metal implant etc.); (2) Psychiatric illnesses; (3) Physical ailments; (4) Intellectual impairment (IQ<90); (5) Received medication treatment recently; (6) Received psychoterapy or TMS intervation on the last 6 months.

Design outcomes

Primary

Measure	Time frame
craving;qEEG;	—

Secondary

Measure	Time frame
clinical outcomes;Cognitive task measures;adverse effects;neuropsychological measures;	—

Countries

China

Contacts

Public ContactTifei Yuan

Shanghai Mental Health Center

ytf0707@126.com+86 18614086633

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026