Neuroblastoma
Conditions
Interventions
Gold Standard:Clinical outcome
Index test:A 
prediction 
model 
based 
on 
machine 
learning 
and 
deep 
data 
for 
the 
construction 
of 
Sponsors
Xinhua Hospital Affiliated to Medical College of Shanghai Jiaotong University
Eligibility
Sex/Gender
All
Age
No minimum to 12 Years
Inclusion criteria
Inclusion criteria: 1. The patients whose pathology and imaging meet the diagnostic criteria of neuroblastoma in the expert consensus on diagnosis and treatment of neuroblastoma in children, 2. Age: 1-12 years old, regardless of gender; 3. The family members of the children signed informed consent and voluntarily accepted blood collection.
Exclusion criteria
Exclusion criteria: 1. Patients with other serious genetic diseases, immune deficiency diseases or organ transplantation diseases; 2. Patients with poor general condition and expected survival time less than 6 months; 3. Patients who have previously received chemotherapy or tumor targeted therapy (i.e. radiotherapy, biological agents, local therapy (embolization, radiofrequency ablation and laser therapy) at the initial diagnosis; 4. Patients with severe infection.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 5-year event-free survival rate;SEN, SPE, ACC, AUC of ROC, PPV, NPV; | — |
Countries
China
Contacts
Public ContactKai Chen
Xinhua Hospital Affiliated to Medical College of Shanghai Jiaotong University
Outcome results
None listed