Repair and reconstruction of defective tissue in children with hypospadias during urethroplasty
Conditions
Interventions
Experimental group:of urethral repair mesh
Control group:Nil
Sponsors
Beijing Children's Hospital Affiliated to Capital Medical University
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: 1. Aged <=5 years, male children; 2. Patients with congenital hypospadias were classified as intermediate type or proximal type; 3. For children who need urethral reconstruction and one-stage urethroplasty, the operation site is the first operation and the operation method is Duckett operation; 4. The patients with hypospadias should be treated with transverse urethral plate; 5. Preoperative examination of patients in accordance with the indications of the operation; 6. Patients who did not participate in other clinical trials within three months before the start of this trial; 7. Patients who voluntarily participate in and sign informed consent after obtaining full information.
Exclusion criteria
Exclusion criteria: 1. Patients with cryptorchidism; 2. Patients with glans width less than 1 cm; 3. The patients were treated with testosterone or androgen before operation; 4. Children who need Duplay operation; 5. Patients with severe liver diseases / systemic hematologic disorders; 6. For patients with severe heart disease and cardiac insufficiency, the researchers judged that they were not suitable for surgery; 7. The patients who used hormone continuously in the last three months were those who used immunosuppressant for a long time; 8. Patients with mental illness or mental disorder; 9. Patients with poor compliance and unable to carry out relevant examination and follow-up according to the test requirements; 10. Other children who did not meet the inclusion criteria determined by the researchers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Effective in preventing urethral fistula; | — |
Secondary
| Measure | Time frame |
|---|---|
| Effective in preventing urethral diverticulum dilation; | — |
Countries
China
Contacts
Public ContactNing Sun
Beijing Children's Hospital Affiliated to Capital Medical University
Outcome results
None listed