Knee osteoarthritis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients aged 50-80 years old; 2. The diagnosis of knee osteoarthritis was in accordance with the diagnostic criteria of Western medicine; 3. Patients who meet the syndrome differentiation standard of dampness heat obstruction syndrome; 4. Patients with knee osteoarthritis of Kellgren Lawrence grade 0 - III; 5. Patients who stop taking NSAIDs for at least 7 days or more; 6. Patients who need to stop taking drugs for one month or more if they use the drugs to improve their condition (diacerein and similar drugs); 7. Patients and their family members have good compliance and sign informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients overlap other rheumatic diseases, such as systemic lupus erythematosus, Sjogren's syndrome, rheumatoid arthritis, etc; 2. Patients with serious diseases such as heart, brain, liver, kidney and hematopoietic system; 3. Pregnant or lactating women, psychotic patients; 4. Patients who have participated in other clinical trials in the past four weeks.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VAS; | — |
Secondary
| Measure | Time frame |
|---|---|
| Michel Lequesen knee OA severity index;Western Ontario McMaster Universities Osteoarthritis Index;Health assessment questionnaire;TCM Syndrome Points;Skin temperature; | — |
Countries
China
Contacts
Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine