Thyroid glands tumor
Conditions
Interventions
Gold Standard:The final pathologic diagnosis from the subjects’ paraffin embedded, formalin fixed surgical specimens will be the golden standard of this study.
Subjects’ surgical paraffin embedded, fo
Index test:The 
mutation, 
indel, 
possibly 
in 
22 
tumor 
genes.
Sponsors
Ruijin Hospital Affiliated to Medical College of Shanghai Jiaotong University
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1. 250 eligible subjects will be tested in this project; 2. The age of detection is more than 18 years old, with no gender limit; 3. Subjects with one or more thyroid nodules; 4. Be willing to provide samples for gene testing with consent; 5. Cell smears were made after puncture; 6. After diagnosis by cytologists, the samples with Bethesda grade III, IV and V were detected by high-throughput gene sequencing.
Exclusion criteria
Exclusion criteria: Nil
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| point mutation;indel;fusion;SEN, SPE, ACC, AUC of ROC; | — |
Countries
China
Contacts
Public ContactLei Dong
Ruijin Hospital Affiliated to Medical College of Shanghai Jiaotong University
Outcome results
None listed