Study on the correlation between proportion of time to target glucose (TIR) and mortality risk in patients with type 2 diabetes mellitus

Association of time in range, a novel measure of glycemic control, with mortality in type 2 diabetes: a prospective cohort study

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2000037067

Enrollment

Unknown

Registered

2020-08-26

Start date

2020-10-01

Completion date

Unknown

Last updated

2020-10-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 diabetes

Interventions

case series:Nil

Eligibility

Sex/Gender

Male

Age

50 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. Patients over 50 years old; 2. Patients with Shanghai household registration; 3. Patients with stable hypoglycemic therapy in recent 3 months; 4. Patients with at least one hospitalization data (baseline) and complete CGM data between June 2005 and June 2020.

Exclusion criteria

Exclusion criteria: 1. Patients with diabetic ketoacidosis and hyperosmolarity recently (within 3 months before enrollment); 2. Patients with recurrent or severe hypoglycemia events in recent years; 3. Patients with recent acute infection, trauma and other stress events; 4. Patients with liver and kidney dysfunction (alanine aminotransferase or aspartate aminotransferase or direct bilirubin higher than 3 times of the normal upper limit, or serum creatinine > 250 µ mol / L).

Design outcomes

Primary

Measure	Time frame
All-cause mortality;	—

Secondary

Measure	Time frame
Cardiovascular mortality;	—

Countries

China

Contacts

Public ContactLu Jingyi

Shanghai Sixth People's Hospital

lujingy1@126.com+86 18930170227

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026