The study on the correlation between NK cell immune factors and pathogenesis of human cytomegalovirus retinitis in AIDS

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2000037066

Enrollment

Unknown

Registered

2020-08-26

Start date

2020-10-01

Completion date

Unknown

Last updated

2020-10-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Human cytomegalovirus retinitis in AIDS

Interventions

CMVR group vs non-CMVR group:Nil

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Male or female patients aged 18-60 years old; 2. HIV positive cases, including CMVR confirmed patients into the experimental group, non CMVR confirmed patients into the control group; 3. Patients who can fully understand the content of informed consent and voluntarily sign the written informed consent form; 4. Patients who can receive follow-up visit, follow-up examination and specimen collection on time; 5. Patients suitable for and receiving stem cell transplantation; 6. Patients without food allergy.

Exclusion criteria

Exclusion criteria: 1. Patients with a history of ocular inflammation; 2. Patients diagnosed with CMVR but having received clinical antiviral treatment of CMVR; 3. Other patients who are considered unsuitable for the study.

Design outcomes

Primary

Measure	Time frame
vision;view filed;Eye B-mode ultrasonography;optical coherence tomography;intraocular pressure;vitreous opacitees;Retinal hemorrhagic lesion;HIV RNA load in the blood;CMV DNA load;CMV-IgG;CMV-IgM;CD4+ lymphocyte count;	—

Countries

China

Contacts

Public ContactYixiong Zhou

The Ninth People's Hospital Affiliated to medical school of Shanghai Jiaotong University

35267130@qq.com+86 13621666684

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026