Congenital heart disease
Conditions
Interventions
Sponsors
The International Peace Maternity & Child Health Hospital of China Welfare Institute
Eligibility
Sex/Gender
Female
Age
20 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1. Serum samples of pregnant women at 12-16 weeks and 24-28 weeks of gestation were collected and followed up to the birth of the newborn. The case data, the results of ultrasound and the data of birth defects were retrospectively inquired. 2. Case group: The serum of pregnant women with congenital heart disease (tetralogy of Fallot, ventricular septal defect and atrial septal defect) in different gestational periods were selected; 3. Control group: The same pregnancy serum of normal pregnant women excluding preeclampsia, gestational diabetes mellitus, gestational hypertension and other pregnancy complications was used, 4. Research period was divided into two periods, namely 12-16 weeks of gestation and 24-28 weeks of gestation; each pregnancy period included four groups, namely tetralogy of Fallot group, ventricular septal defect group, atrial septal defect group and fetal group without obvious abnormality (tracking to postpartum).
Exclusion criteria
Exclusion criteria: None
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Maternal serum exosome miRNA;Sensitivity;Specificity;Specificity;Specificity; | — |
Countries
China
Contacts
Public ContactHaiou Yang
The International Peace Maternity & Child Health Hospital of China Welfare Institute
Outcome results
None listed