Senile Hypertension
Conditions
Interventions
Sponsors
Yueyang Hospital of Intergrated Traditional Chinese and Western Medicine,Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Old age is defined as age >= 60 years old. two. Meet the diagnostic criteria of essential hypertension. 3. Before the test, ambulatory blood pressure examination showed at least one of the following abnormalities: 24-hour average systolic or diastolic blood pressure was not up to standard, early morning hypertension, abnormal circadian rhythm of blood pressure, abnormal blood pressure variability. 4. Understand and agree to participate in this study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients with malignant hypertension. 2. Patients with severe cardiovascular and cerebrovascular diseases and respiratory diseases. 3. Patients with severe abnormality of liver and kidney function, malignant tumor and anemia. 4. Patients with mental illness and patients who are unable to describe their symptoms and have difficulties in understanding. 5. Patients who are allergic to the drugs used in this study. 6. Women during pregnancy and lactation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mean of 24-hour blood pressure;TCM syndrome score;Blood pressure load;Blood pressure variability;Blood pressure circadian rhythm; | — |
Secondary
| Measure | Time frame |
|---|---|
| Detection of microRNA in serum;Detection of inflammatory factors in peripheral blood monocytes;Detection of intestinal flora abundance in feces;Serum homocysteine;Serum C-reactive protein;Target organ damage index;Serum creatinine;Urinary Microalbumin / urinary creatinine ratio; | — |
Countries
China
Contacts
Public ContactZhangTeng
Yueyang Hospital of Intergrated Traditional Chinese and Western Medicine,Shanghai University of Traditional Chinese Medicine
Outcome results
None listed