The predictive value of gut permeability in children with steroid dependent nephrotic syndrome

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2000037014

Enrollment

Unknown

Registered

2020-08-26

Start date

2020-10-01

Completion date

Unknown

Last updated

2020-09-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Primary nephrotic syndrome

Interventions

Steroid sensitive nephrotic syndrome group (SSNS group):Prednisone treatment recommended by the guidelines

Steroid dependent nephrotic syndrome group (SDNS group):Prednisone treatment recommended by the guidelines

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Children with onset primary nephrotic syndrome (PNS) are not treated before recruitment. Onset age 2-18 years old. The gender is not limited.

Exclusion criteria

Exclusion criteria: (1) PNS patients with other organ diseases. (2) Abnormal renal function (eGFR<90ml/min.1.73m^2).

Design outcomes

Primary

Measure	Time frame
Recurrence times;Ratio of urinary proteinuria and creatinine;Serum zonulin;Serum albumin;SEN, SPE, ACC, AUC of ROC;	—

Countries

China

Contacts

Public ContactKang Yulin

Department of Nephrology and Rheumatology, Shanghai Children's Hospital

kangyulinmed@126.com+86 18221992381

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026