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Clinical study of a new liposome nanofibers patch for transdermal drug delivery containing ebracteolata Hayata in the treatment of actinic keratosis

Clinical study of a new liposome nanofibers patch for transdermal drug delivery containing ebracteolata Hayata in the treatment of actinic keratosis

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000036997
Enrollment
Unknown
Registered
2020-08-26
Start date
2020-10-01
Completion date
Unknown
Last updated
2020-09-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

actinic keratosis

Interventions

experimental group:Drugs for external use
control group:Placebo for external use

Sponsors

Shuguang Hospital affiliated to Shanghai University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
14 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1. In line with the clinical diagnostic criteria of solar keratosis in western medicine (refer to Andrews Clinical Dermatology, 10th edition, Science Press, 2008, 2nd edition, 678 pages, clinical manifestations of solar keratosis as diagnostic criteria), all patients were diagnosed by dermatoscopy and pathological biopsy. 2. Good compliance and sign informed consent.

Exclusion criteria

Exclusion criteria: 1. Pregnant and lactating women; 2. Persons with diseases of the immune system; 3. Allergic to drug ingredients; 4. Patients who had received any physical therapy or topical medication in the first four weeks of the trial; 5. Patients with severe primary diseases such as cardiovascular, cerebrovascular, liver, kidney and hematopoietic system, and psychosis; 6. Discontinue or change the tested drugs and methods at will during the study period; 7. Failure to follow the prescribed medication, inability to judge the efficacy, or incomplete data affecting the efficacy or safety judgment.

Design outcomes

Primary

MeasureTime frame
Dermatitis clearance rate;

Countries

China

Contacts

Public ContactXiang He

Shuguang Hospital affiliated to Shanghai University of Traditional Chinese Medicine

heroxiang@hotmail.com+86 13681737694

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026