Diabetes
Conditions
Interventions
MACE group, LEAD group, DR group, DN group:N/A
Sponsors
Shanghai Sixth People's Hospital
Eligibility
Sex/Gender
All
Age
60 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Type 2 diabetes above 60 years old with at least 2 cardiovascular risk factors below: a) Smoking; b) Patients with low or low density lipoprotein cholesterol (>= 3.4mmol /L) who received lipid-lowering treatment within 6 months or were diagnosed but not treated; c) High-density lipoprotein cholesterol = 2.3mmol /L; d) Treatment for hypertension, or untreated increase in blood pressure (systolic pressure >= 140 mmHg or diastolic pressure >= 95 mmHg); e) Waist-hip ratio > 1.0 (male) or > 0.8 (female); 2. HbA1c and GA were measured >= 3 times within 2 years before admission; 3. Signed the informed consent.
Exclusion criteria
Exclusion criteria: 1. Diabetic ketoacidosis, malignant tumor, autoimmune disease, blood diseases and a history of mental illness, severe liver and kidney dysfunction; 2. History of alcohol/drug abuse; 3. Long-term use of hormone or steroids therapy; 4. Pregnancy; 5. Patients planning to receive bariatric surgery; 6. Severe anemia and hypoproteinemia.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Diabetes Retinopathy;microalbuminuria;estimated glomerular filtration rate; | — |
Primary
| Measure | Time frame |
|---|---|
| glycated hemoglobin variability;glycated albumin variability;Intimal medial thickness of peripheral artery;Major adverse cardiovascular events; | — |
Countries
China
Contacts
Public ContactZhou Jian
Shanghai Sixth People's Hospital
Outcome results
None listed