schizophrenia
Conditions
Interventions
Group A:tACS-theta
Group B:tACS-gamma
Group C:tACS-sham
Sponsors
Shanghai Mental Health Center
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Subjects who have cognitive deficits as indicated by a score of < 85 on RBANS, and meet criteria for DSM-5 diagnosis of chronic schizophrenia(SZ), schizoaffective disorder (SA), or schizophreniform disorder (SZF), who are stably treated with antipsychotic medications and are not in acute exacerbation of illness symptoms (PANSS <= 60), and who are able to provide written informed consent.
Exclusion criteria
Exclusion criteria: 1. Combined with other psychiatric disorders, 2. With serious or unstable medical illness; 3. With risk factors for an MRI scan; 4. Aalcohol abuse within the past 30 days or diagnosis of alcohol or substance dependence within the past 6 months; 5. For women of childbearing age who are pregnant or regularly engaging in sexual activity and not regularly using an acceptable birth control method (systemic or double-barrier); 6. Prior treatment of modified ECT within the past 1 month; 7. Prior attendance of other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| changes in The MATRICS Consensus Cognitive Battery;changes in Neuroimage changes in Magnetic Resonance Imaging;changes in electroencephalogram; | — |
Secondary
| Measure | Time frame |
|---|---|
| The Paced Auditory Serial Addition Task;The Positive and Negative Syndrome Scale;the UCSD Performance-Based Skills Assessment Battery Brief edition; | — |
Countries
China
Contacts
Public ContactXinyi Cao
Shanghai Mental Health Center
Outcome results
None listed