Surgical Site Infection
Conditions
Interventions
neoadjuvant therapy group vs non neoadjuvant therapy group:Nil
infection group vs non infection:Nil
Sponsors
Shanghai Chest Hospital
Eligibility
Sex/Gender
All
Age
20 Years to 90 Years
Inclusion criteria
Inclusion criteria: Same criteria: 1. Cases with complete medical history; 2. The selected products for preventive use of antibiotics were the first generation cefazolin or the second generation cefoxime, and the dose and course of treatment were in line with the Guidelines for Clinical Application of Antibiotics (2015 edition); 3. The timing of prophylactic use of antimicrobial agents was 0.5-2h before operation; 4. Operation duration < 3 hours, and intraoperative blood loss < 1500mL. Different criteria: 1. Case group: cases receiving neoadjuvant therapy (including chemotherapy, targeting or immunization). 2. Control group: patients without neoadjuvant therapy.
Exclusion criteria
Exclusion criteria: 1. Cases of allergy to -lactam antibiotics; 2. The course of prophylactic use of antibiotics without postoperative infection is >= 48 hours; 3. Patients who received non-prophylactic antimicrobial therapy after the operation were asymptomatic; 4. Neoadjuvant therapy regimens containing radiotherapy; 5. Cases treated with antibiotics 2 weeks before operation; 6. Pet-type cases with severe insufficiency of liver and kidney function; 7. The case of secondary surgery on the lung.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| DDDs of antibiotics use during hospitalization; | — |
Secondary
| Measure | Time frame |
|---|---|
| Proportion of antibiotics used in special use grade; | — |
Countries
China
Contacts
Public ContactYu Jianguang
Shanghai Chest Hospital
Outcome results
None listed