nonalcoholic steatohepatitis
Conditions
Interventions
Sponsors
Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Participate and sign the informed consent form voluntarily; 2. The age ranged from 18 to 60 years old; 3. According to the diagnosis of nonalcoholic steatohepatitis, the liver fat content was more than 5%, ALT 1 x ULN; 4. Those who have not used other drugs for the treatment of nonalcoholic steatohepatitis within 3 months.
Exclusion criteria
Exclusion criteria: 1. Nash related cirrhosis; 2. LDL > 4.14 mmol/L (indication for statins) or TG>5.6mmol/L (indication for fibrates); 3. Those who are using heparin, thyroxine and other drugs that affect fat metabolism; 4. Serious primary cardiovascular, liver, kidney, lung and hematological diseases, or serious diseases affecting survival, such as tumor or AIDS; 5. Pregnant and lactating women; 6. Those who have mental disorders can not give full informed consent; 7. People with allergic constitution or known to be allergic to the components of the drug; 8. Patients receiving other trial drugs within 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Analysis of liver fat content by magnetic resonance imaging;liver CAP value;liver function (ALT, AST, AKP, GGT); | — |
Secondary
| Measure | Time frame |
|---|---|
| CK18 level;blood lipids;blood sugar;Insulin resistance index;weight;Body Mass Index;waist-hip ratio;NAFLD liver fibrosis score;APRI; | — |
Countries
China
Contacts
Public ContactLyu Jing
The Institute of Liver Disease, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine
Outcome results
None listed