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Establishment of evaluation system of toxicity and side effects of chemotherapy for colorectal cancer and development of new early warning markers related to therapeutic effect

Establishment of evaluation system of toxicity and side effects of chemotherapy for colorectal cancer and development of new early warning markers related to therapeutic effect

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000036902
Enrollment
Unknown
Registered
2020-08-25
Start date
2020-10-01
Completion date
Unknown
Last updated
2020-09-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

colorectal cancer

Interventions

Sponsors

Shanghai Changzheng Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Aged 20-80 years old; 2. Karnofsky score >=80; 3. Primary colorectal malignant tumor confirmed clinically and pathologically, and underwent radical operation. 4. the classic second-line regimen FOLFIRI is applied to patients whose first-line regimen is ineffective or unable to receive first-line regimen; 5. patients and their families can understand the study plan and are willing to participate in this study and provide written informed consent.

Exclusion criteria

Exclusion criteria: 1. ASA level IV to V; 2. receive neoadjuvant therapy (such as radiotherapy and chemotherapy, targeted therapy, etc.); 3. pregnant or lactating women; 4. severe cardiovascular disease, uncontrollable infection, or other uncontrollable concomitant diseases; 5. complicated with a history of other multiple tumor diseases or other hereditary diseases; 6. patients or their families cannot understand the conditions and objectives of this study.

Design outcomes

Primary

MeasureTime frame
toxic and adverse effects;

Countries

China

Contacts

Public ContactZhiqian Hu

Shanghai Changzheng Hospital

huzhiq163@163.com+86 15021793681

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026