Macronodular cirrhosis after chronic hepatitis B
Conditions
Interventions
Sponsors
Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Patients with chronic hepatitis B cirrhosis who meet the diagnostic criteria; 2. Hepatic regenerative nodules (>5 mm) were detected by Contrast enhanced ultrasound; 3. Aged 18 to 65 years; 4. Sign informed consent.
Exclusion criteria
Exclusion criteria: (1) Patients with cirrhosis caused by other hepatophilic virus infection or other pathogenic factors; (2) The presence or suspected presence of primary hepatocellular carcinoma lesions was detected by B-mode ultrasonography or MRI; (3) The patients with Child-Pugh C grade > 12 points, had upper gastrointestinal bleeding, hepatic encephalopathy and hepatorenal syndrome in the past six months; (4) Patients with severe primary diseases of heart, kidney, lung, endocrine, blood, metabolism and gastrointestinal tract; or psychiatric patients; (5) Pregnant women or breast-feeding women who are willing to have children in the near future.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of primary liver cancer;Incidence and mortality of severe hepatitis;Incidence of upper gastrointestinal hemorrhage, hepatic encephalopathy and hepatorenal syndrome; | — |
Secondary
| Measure | Time frame |
|---|---|
| Virological indicators;Liver function;CBC;Alpha fetoprotein;Contrast enhanced ultrasound;Fibroscan;TCM Syndrome Scale and Quality of Life Scale; | — |
Countries
China
Contacts
Public ContactGao Yueqiu
Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine
Outcome results
None listed