COPD
Conditions
Interventions
control group:Different concentrations of sevoflurane were inhaled according to up-down method
mild pulmonary dysfunction group:Different concentrations of sevoflurane were inhaled according to up-down method
Moderate pulmonary dysfunction group:Different concentrations of sevoflurane were inhaled according to up-down method
Severe pulmonary dysfunction group:Different concentrations of sevoflurane were inhaled according to up-down metho
Sponsors
Affiliated Hospital of North Sichuan Medical College
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: In patients undergoing elective surgery in 100 cases, sexs, aged > 50, cardiac function I- II level, ASA I - III level, has a history of chronic obstructive pulmonary disease (copd). Patients with normal, mild, moderate or severe pulmonary dysfunction were included according to the pulmonary function examination.
Exclusion criteria
Exclusion criteria: Patients with Mallampati grade three to four, and with the history of COPD acute attack within three months, general anesthesia, allergy to halogenated anesthetic drugs, a family history of malignant hyperthermia and heart diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MACawake of sevoflurane in patients with different pulmonary function conditions; | — |
Secondary
| Measure | Time frame |
|---|---|
| Inhalation induced loss of consciousness in patients;Vital signs (HR, RR, NIBP, ETCO2, BIS) at different time points (entry (T0), pre-induction (T1), disappearance of consciousness (T2), maintenance of consciousness at the set concentration of 15min (T3) and full recovery (T4));The occurrence and management of complications; | — |
Countries
China
Contacts
Public ContactQilin Liu
Affiliated Hospital of North Sichuan Medical College
Outcome results
None listed