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Serum exosomal miRNA/LncRNA as potential biomarkers for Early detection and monitoring progression of gastric cancer and observation on therapeutic effect of Traditional Chinese Medicine on gastric precancerous lesions

Serum exosomal miRNA/LncRNA as potential biomarkers for Early detection and monitoring progression of gastric cancer and observation on therapeutic effect of Traditional Chinese Medicine on gastric precancerous lesions

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000036857
Enrollment
Unknown
Registered
2020-08-25
Start date
2020-10-01
Completion date
Unknown
Last updated
2020-09-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastric cancer and precancerous lesions

Interventions

Sponsors

Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 120 cases came from outpatients and inpatients in the Department of Gastroenterology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine. Diagnosis refers to the relevant standards in the "Chinese Consensus on Chronic Gastritis" (Chinese Medical Association Gastroenterology Branch. China Chronic Gastritis Consensus (2017, Shanghai). Gastroenterology, 2017, 22(11):670-687). 1. All participants must meet the above diagnostic criteria, that is, chronic atrophic gastritis, especially patients with moderate to severe intestinal metaplasia or dysplasia (intraepithelial neoplasia); 2. Aged 20 to 75 years old; 3. signed informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients confirmed by pathological examination to have cancer; 2. Patients with major organ diseases, it is difficult to complete the clinical trial program; 3. Patients with mood disorders and cognitive disorders; 4. Patients during pregnancy and lactation.

Design outcomes

Primary

MeasureTime frame
Electronic gastroscope;Pathology;Pepsinogen;Serum exosomal miRNA/LncRNA;

Countries

China

Contacts

Public ContactXiuli Yan

Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine

yxl9999@126.com+86 13764993708

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026