post-stroke cognitive impairment
Conditions
Interventions
TMS group:transcranial magnetic stimulation+ cognitive training
tDCS group:transcranial direct currents stimulation+ cognitive training
cognitive training group:none
health control group(tDCS):transcranial direct currents stimulation
health control group(TMS):Transcranial magnetic stimulation
Sponsors
Huashan Hospital, Fudan University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Post-Stroke Cognitive Impairment Patients: 1. Aged 18 to 75 years; 2. Post cerebral infarction or cerebral hemorrhage, onset time 1 to 12 months; 3. Patients with Cerebrovascular diseases; 4. Patients with first stroke or previous stroke without sequelae; 5. Confirmed stroke by head CT or MRI, and exclude obvious neuropathies (such as encephalitis, hydrocephalus, etc.; 6. Cognitive impairment; 7. Cooperate for cognitive test, training, and follow-up; 8. Signed informed consent by the patient or direct family members.? Health Volunteers: 1.Aged 18 to 75 years; 2.Without severe visual or hearing impairment. 3.Without cognitive impairment; 4.Signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients accompanied by unconsciousness, could not cooperate with the examination and treatment; 2. Patients with severe primary diseases in heart, liver, kidney and hematopoietic system; 3. Patients with cognitive impairment due to other non-cerebrovascular diseases; 4. Previous history of mental disorders, substance abuse; 5. Patients with organ failure or severity stroke and cancer and other diseases or conditions that affect the quality of life of patients more than post-stroke cognitive impairment; 6. Patients who are unable to complete treatment, may have poor compliance and difficult to follow up.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Functional Near-Infrared Spectroscopy, fNIRS;Electroencephalography, EEG; | — |
Secondary
| Measure | Time frame |
|---|---|
| Mini-Mental State Examination,MMSE;The Montreal Cognitive Assessment, MoCA;activity of daily living, ADL;The Zung Self-Rating Anxiety Scale, SAS;The Zung Self-Rating Depression Scale, SDS;Auditory Verbal Learning Test, AVLT;Rey-Osterrieth Complex Figure Test, CFT;Clock drawing test, CDT;Boston naming test, BNT;verbal fluency test, VFT;Trail Making Test, TMT; | — |
Countries
China
Contacts
Public ContactWu Yi
Department of Rehabilitation Medicine, Huashan Hospital, Fudan University
Outcome results
None listed