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A single-center, non-blind, randomized controlled trial to evaluate the efficacy and safety of new subglottic suction airway and traditional subglottic suction airway in the prevention of ventilator associated pneumonia in patients with severe craniocerebral injury

A single-center, non-blind, randomized controlled trial to evaluate the efficacy and safety of new subglottic suction airway and traditional subglottic suction airway in the prevention of ventilator associated pneumonia in patients with severe craniocerebral injury

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000036844
Enrollment
Unknown
Registered
2020-08-25
Start date
2020-10-01
Completion date
Unknown
Last updated
2020-09-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ventilator-associated pneumonia

Interventions

Experimental group:New subglottic suction technology
Control group:Conventional treatment

Sponsors

Shanghai First People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1) Having typical clinical symptoms and a definite history of trauma; 2) Skull CT examination confirmed organic brain injury and GCS score 2d.

Exclusion criteria

Exclusion criteria: 1) Patients with overdose of psychotropic drugs or acute intoxication; 2) Patients with malignant diseases or inflammation; 3) Lactating or pregnant women; 4) Patients admitted to hospital after cardiac arrest; 5) Patients who have been mechanically ventilated for more than 24 hours or who have participated in another trial; 6) Patients who had undergone tracheotomy or intubation before ICU admission, but not SSD artificial airway; 7) Mechanical ventilation is expected to be shorter than 48h; 8) Estimated survival time <5d.

Design outcomes

Primary

MeasureTime frame
Level of first-class hospital;—

Countries

China

Contacts

Public ContactWu Shaohong

Shanghai First People's Hospital

wshsuda@aliyun.com+86 17717688539

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026