extrahepatic portal venous obstruction (EHPVO)
Conditions
Interventions
Group 1:Portal-to-right portal vein bypass operation
Group 2:Portal-to-left portal vein bypass operation
Sponsors
Capital Institute of Pediatrics
Eligibility
Sex/Gender
All
Age
No minimum to 18 Years
Inclusion criteria
Inclusion criteria: 1. The age ranged from newborn to 18 years old; 2. cavernous transformation of portal vein was diagnosed by ultrasound or CT; 3. Suffering from the gastrointestinal bleeding; 4. Suffering from hypersplenism; 5. the well-developed intrahepatic left and right portal vein developed well with a diameter of >= 2mm.
Exclusion criteria
Exclusion criteria: 1) portal hypertension caused by liver fibrosis; 2) the occluded left portal vein occlusion or its diameter is less than 2 mm; 3) the diameter of right portal vein is less than 2 mm; 4) The children undergoing a failure Rex shunt.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The patency rate of bypass vein;The size of spleen;The patency rate of bypass vein;The size of spleen;Liver Volume;esophageal varices;esophageal varices;routine blood test;Biochemistry test;Coagulation function;Portal pressure;postoperative re-bleeding;Protein C;Protein S;antithrombin 3;The diameter of bypass vein; | — |
Secondary
| Measure | Time frame |
|---|---|
| The time of feeding;postoperative bleeding;postoperative hospital stay;Operation cost;Operative time; | — |
Countries
China
Contacts
Public ContactLong Li
Capital Institute of Pediatrics
Outcome results
None listed