Atrial fibrillation
Conditions
Interventions
Experimental Group:Stereotactic radiation therapy
Control:Radiofrequency ablation
Sponsors
Huashan Hospital affiliated to Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1. having a history of atrial fibrillation or having atrial fibrillation attack during hospitalization and definite diagnosis of atrial fibrillation by ECG / Holter. The diagnostic criteria of atrial fibrillation were: P wave disappeared on ECG or Holter, and F wave with irregular amplitude, shape and spacing was replaced by irregular ventricular wave; 2. aged >18 years old; 3. sinus rhythm could not be maintained by drugs; 4. persistent atrial fibrillation was diagnosed more than 1 year, or persistent atrial fibrillation combined with significant left atrial enlargement (length diameter >=50 mm); 5. patients with persistent atrial fibrillation who failed to receive radiofrequency ablation and refused to accept radiofrequency ablation treatment.
Exclusion criteria
Exclusion criteria: 1. atrial fibrillation caused by valvular disease; 2. with mediastinal and pulmonary lesions; 3. congenital and rheumatic heart disease; 4. history of myocardial infarction; 5. pulmonary vein structure was affected by other diseases except atrial fibrillation; 6. CTA could not be performed due to contrast medium allergy or other reasons; 7. patients with uncontrollable hyperthyroidism, obvious abnormal liver and kidney function, tumor diseases, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| adverse event;AF BURDEN; | — |
Secondary
| Measure | Time frame |
|---|---|
| quality of life(QoL)SF -12; | — |
Countries
China
Contacts
Public ContactXinping Luo
Huashan Hospital affiliated to Fudan University
Outcome results
None listed