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The application value of CT perfusion imaging in advanced hepatocellular carcinoma patients with antiangiogenesis drugs treatment

The application value of CT perfusion imaging in advanced hepatocellular carcinoma patients with antiangiogenesis drugs treatment

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000036786
Enrollment
Unknown
Registered
2020-08-25
Start date
2020-10-01
Completion date
Unknown
Last updated
2020-09-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hepatocellular carcinoma (HCC)

Interventions

Gold Standard:RECIST1.1 criteria

Sponsors

Shanghai General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1) Participated in the study voluntarily and signed the written informed consent; 2) patients aged 18 to 75 years old; 3) The diagnosis of hepatocellular carcinoma conforms to CSCO guidelines; 4) Antivascular drug therapy; 5) Measurable lesions were confirmed by at least two imaging examination methods (including ultrasound, CT, MRI) and digital subtraction angiography (DSA); there was at least one measurable lesion meeting the RECIST 1.1 standard; 6) Child-pugh grade A or B for liver function; 7) The functions of the heart, kidney, bone marrow and other important organs are basically normal; 8) The patient's physical status is according to the Eastern Cooperative Oncology Group, ECOG) score 0-2; 9) The patient's expected survival time is more than 2 months.

Exclusion criteria

Exclusion criteria: 1) Active brain metastasis, cancerous meningitis, spinal cord compression; 2) Obvious cavitation or necrosis within the tumor; 3) Uncontrolled infection; 4) Poor control of serous cavity effusion; 5) A clear neurological or psychiatric history, including epilepsy or dementia; 6) Patients with iodine allergy; 7) Other exclusion criteria Refer to standard clinical study requirements.

Design outcomes

Primary

MeasureTime frame
CTP parameters;

Countries

China

Contacts

Public ContactFan Wang

Shanghai General Hospital

fairywong04285@163.com+86 13564260428

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026