Chronic obstructive pulmonary disease
Conditions
Interventions
Gold Standard:Clinical outcome
on 
the 
blast 
verification, 
used 
RPA 
and 
technology 
to 
acid 
Sponsors
Shanghai Pulmonary Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Aged over 40 years male or female; 2. According to the chronic obstructive pulmonary disease guidelines (2018 edition) , after inhalation of Bronchodilator, FEV1FVC <70% were the diagnostic criteria of chronic obstructive pulmonary disease, and 200 patients with chronic obstructive pulmonary disease were selected; 3. Acute exacerbation of chronic obstructive pulmonary disease (AECOPD) is defined as dyspnea, cough, increased sputum or purulent sputum at night, exceeding the daily variation, according to the consensus of Chinese experts on the diagnosis and treatment of acute exacerbation of chronic obstructive pulmonary disease (AECOPD)(revised edition 2017), patients who need to change their treatment.
Exclusion criteria
Exclusion criteria: 1. Unable to cooperate with the patient to take the qualified deep part sputum specimen. 2. Sputum Culture confirmed that lower respiratory tract infection was the most common pathogen except for other pathogens. 3. Rule out acute pulmonary edema, acute pulmonary embolism, acute heart failure, Arrhythmia, and other heart and lung diseases; 4. Rule out the combination of tumor, autoimmune disease, etc. 5. Patients with asthma, tuberculosis, Interstitial lung disease, and other chronic lung diseases were excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Characteristic sequence detection of pathogenic bacteria nucleic acid;MMAC score;Arterial blood gas analysis;Pathogen detection time;SEN, SPE, ACC, AUC of ROC; | — |
Secondary
| Measure | Time frame |
|---|---|
| Length of stay;medical expense; | — |
Countries
China
Contacts
Public ContactJina Ma
Shanghai Pulmonary Hospital
Outcome results
None listed