The application of Left bundle-branch pacing in patients with atrioventricular block

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000036775

Enrollment

Unknown

Registered

2020-08-25

Start date

2021-01-01

Completion date

Unknown

Last updated

2020-09-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

AVB

Interventions

experimental group:Left bundle-branch pacing

control group:Right septal pacing

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (1) Grade II II AV block and grade III AV block with symptomatic grade III AV block, per the 2018 ESC guidelines. (2) New York Heart Association (NYHA) class II or III with left ventricular ejection fraction (LVEF) >= 40% on cardiac ultrasound. (3) ECG suggesting a self QRS wave width of <=130ms. (4) Aged over 18 and under 80 years. (5) The place of residence is relatively stable and follow-up requirements can be met for the duration of the clinical study.

Exclusion criteria

Exclusion criteria: (1) Intraventricular conduction block or bundle branch block. (2) Patients with right ventricular mechanical valves. (3) Patients with or awaiting a heart transplant. (4) Patients with severe hepatic or renal insufficiency. (5) Severe chronic obstructive pulmonary disease. (6) Life expectancy of less than one year. (7) have been enrolled in other clinical studies that may affect the purpose of this study.

Design outcomes

Primary

Measure	Time frame
LVEF;	—

Countries

China

Contacts

Public ContactRuogu Li

Shanghai Chest Hospital, Shanghai Jiao Tong University

lrg@sjtu.edu.cn+86 13564565961

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026