aMCI
Conditions
Interventions
Sponsors
Longhua Hospital, Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
Female
Age
40 Years to 60 Years
Inclusion criteria
Inclusion criteria: (1) 40~60 years old (including 60 years old); (2) Meet the diagnostic criteria of western medicine for menopausal syndrome and MCI; (3) Patients with deficiency of kidney yin and deficiency of both kidney yin and yang that meet the TCM syndrome differentiation standards; (4) 1 year <menopausal time < 9.5 years; (5) Those who voluntarily participated in this study.
Exclusion criteria
Exclusion criteria: (1) Patients with severe heart, liver, kidney, brain and other organic diseases and severe physical diseases and malignant tumors; (2) Patients with active thyroid disease; (3) Those who are allergic to known pharmaceutical ingredients; (4) Patients with severe depression (Beck Depression Inventory BDI-II score> 28 points); (5) Exclude people with cognitive dysfunction caused by trauma, brain tumors and surgery; (6) Alcohol and drug abusers; (7) Patients who have used banned drugs in the past 3 months or participated in other clinical trials; (8) Patients with folic acid and vitamin B12 deficiency.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Wechsler Memory Scale;Auditory Vocabulary Learning Test Huashan Version;MoCA Scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Evaluation of menopausal symptoms;Sleep quality assessment;TCM symptom assessment;Metabolic index evaluation;Serum sex hormone assessment; | — |
Countries
China
Contacts
Public ContactLianwei Xu
Longhua Hospital,Shanghai University of Traditional Chinese Medicine
Outcome results
None listed