Hip Fractures
Conditions
Interventions
DG:Dexmedetomidine was intravenously administered before surgery
RG:On the day before the operation, the posterior lumbar plexus block was performed by an experienced anesthesiologist
RDG:continuous lumbar plexus block one day before the surgery, Dexmedetomidine was intravenously administered before surgery
Sponsors
Shanghai General Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Elderly patients with hip fracture who receive elective surgical treatment; 2) Aged 65 years and above; 3) ASA I ~ III; 4) Sign informed consent.
Exclusion criteria
Exclusion criteria: 1) Cmpound injury: multiple fractures, combined with trauma of the head, chest, abdomen, pelvis and other parts other than the hip; 2) Contraindications for lumbar plexus block: puncture site infection, peripheral neuropathy, local anesthetic allergy, etc.; 3) Co-existing neurological diseases: alzheimer's disease, vascular dementia and other diseases that affect the cognitive function of patients; 4)MMSE < 24; 5) Unable to communicate normally, language communication barrier, illiterate and illiterate; 6) There is an allergy to the test drug; 7) Have participated in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| POD; | — |
Secondary
| Measure | Time frame |
|---|---|
| type and severity of POD;postoperative pain;postoperative inflammatory biomarkers;postoperative complications;drug use;mortality;quality of life; | — |
Countries
China
Contacts
Public ContactJinbao Li
Shanghai General Hospital
Outcome results
None listed