Dentition defect
Conditions
Interventions
A:Basic treatment of osteoporosis (oral calcium tablets and vitamin D) was started 1 month before operation
B:Before implantation, teripaptide was given basic treatment for osteoporosis for 1 month
C:After the operation, only basic treatment of osteoporosis was given
D:After implantation, teripagin was given basic treatment for osteoporosis for 1 month
Sponsors
Ruijin Hospital, Affiliated to the School of Medicine, Shanghai Jiaotong University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) patients with clinically diagnosed dentition defect have more than one dentition defect and need dental implant. 2) the clinical diagnosis was osteoporosis, in accordance with the Teriparatide indications, good oral hygiene and good health; 3) the clinical examination: normal range of Keratinized Gingiva in the edentulous area, good color and mobility of the oral Mucosa. 4) x-ray or CT examination: the bone mass in the edentulous area of the jaw meets the conditions of dental implantation, and no bone graft is needed. 5) bone mineral density (BMD) was less than-2.5. 6) patients gave informed consent and were able to participate in multiple follow-up visits during the study period.
Exclusion criteria
Exclusion criteria: 1) implant patients requiring additional Bone Augmentation Surgery; 2) patients with a history of systemic diseases such as diabetes, cancer, radiation and chemotherapy, abnormal liver and kidney function, and heavy smoking. 3) patients who did not agree to participate in the study and who did not want to follow the study's blind method; 4) the researchers decided that other reasons were not appropriate for the clinical trial participants.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Implant stability;Implant looseness;Marginal bone level of implant;Peri-implant soft tissue level; | — |
Secondary
| Measure | Time frame |
|---|---|
| Bone density;Serological index; | — |
Countries
China
Contacts
Public ContactJiang Liting
Ruijin Hospital, School of Medicine, Shanghai Jiaotong University
Outcome results
None listed