lung cancer
Conditions
Sponsors
Longhua Hospital, Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: (1) Patients with stage IIIA-IV lung adenocarcinoma confirmed by pathology or cytology or patients with postoperative recurrence and metastasis; (2) EGFR detected sensitive types (18, 19, 21 exon mutations); (3) Evaluate the disease progression after 1 month of gefitinib treatment and continue to take it; (4) TCM syndrome differentiation belongs to the deficiency of essence and qi; (5) Aged >= 18 years; (6) Expected survival >= 3 months; (7) Sign the informed consent.
Exclusion criteria
Exclusion criteria: (1) Other tumor history within 5 years; (2) Symptomatic brain metastases; (3) History of cardiovascular disease: Congestive heart failure & GT; Cardiac function level II in NYHA. Patients with unstable angina (angina symptoms at rest) or newly developed angina (beginning in the last 3 months) or myocardial infarction in the last 6 months. Active infection, & GT; Level 2 adverse events (CTC AE.5.0); (4) Patients during pregnancy or lactation; (5) Persons with a history of mental illness.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Overall Survival;Progress Free Survival; | — |
Secondary
| Measure | Time frame |
|---|---|
| Disease Control Rate;duration of disease control;The quality of life;TCM clinical syndromes and symptoms;Serum tumor markers;Lymphocyte subtype; | — |
Countries
China
Contacts
Public ContactWang Zhongqi
Longhua Hospital, Shanghai University of Traditional Chinese Medicine
Outcome results
None listed