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Preclinical study of a new drug for the treatment of cirrhosis and ascites (spleen-kidney yang deficiency) with Babu Ointment and Shuichang Tie acupoint application (grade 2-3)

Preclinical study of a new drug for the treatment of cirrhosis and ascites (spleen-kidney yang deficiency) with Babu Ointment and Shuichang Tie acupoint application (grade 2-3)

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000036724
Enrollment
Unknown
Registered
2020-08-24
Start date
2021-01-01
Completion date
Unknown
Last updated
2020-09-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cirrhosis ascites

Interventions

experimental group:Shuigui Cataplasm external application + Basic Treatment

Sponsors

Shanghai Municipal Hospital of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. It meets the diagnostic criteria for ascites due to liver cirrhosis and the volume of ascites before treatment is 2-3; 2. According to TCM syndrome differentiation of spleen and kidney yang deficiency syndrome; 3. Age between 18 and 70 years old, regardless of gender; 4. Patients fully understand and agree to participate in this trial study, and sign an informed consent form.

Exclusion criteria

Exclusion criteria: 1. The subject has both severe bacterial infection, chronic renal failure and malignant tumor; 2. Patients suffering from upper gastrointestinal bleeding or hepatic encephalopathy in the past 2 weeks; 3. Patients with severe electrolyte disturbance, namely serum potassium < 3.0 mmol/L and serum sodium < 120 mmol/L; 4. Patients with serious primary diseases such as cardio-cerebrovascular, hematopoietic system and mental illness; 5. People with allergies and allergies to the known ingredients of the drug in this study.

Design outcomes

Primary

MeasureTime frame
Ascites volume;Urine output;supine abdominal circumference maximum;weight;

Secondary

MeasureTime frame
Chinese Medical Syndrome scores;liver function;Kidney function;Serum electrolytes;

Countries

China

Contacts

Public ContactZhu Junfeng

Shanghai Municipal Hospital of Traditional Chinese Medicine

zhujftongling@163.com+86 15800398287

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026