Stroke
Conditions
Interventions
healthy control:swallowing observation
Experimental group of patients with dysphagia after stroke:swallowing action observation therapy and routine rehabilitation treatment
Control group of patients with dysphagia after stroke:routine rehabilitation treatment
Sponsors
The Second Affiliated Hospital of South China University of Technology/Guangzhou First People's Hospital
Eligibility
Sex/Gender
All
Age
20 Years to 80 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria for healthy subjects: 1. Good health; 2. No swallowing disorder was found in eat-10 screening; 3. Having the ability to act independently and no speech or cognitive impairment; 4. No neurological or mental system diseases and no head or neck structural lesions; 5. Binocular vision or corrected vision >= 1.0 by international standard visual acuity chart examination; 6. Serious diseases of the organs of the heart, lung, liver, pancreas and kidney; 7. Except for brain atrophy and a small amount of T2WI high signal in deep white matter (maximum diameter = 26 points; 5. Binocular vision or corrected vision >= 1.0 by international standard visual acuity chart examination; 6. The course of illness ranges from 3 to 12 months; 7. Can follow the instructions for inspection; 8. Voluntary sign the informed consent.
Exclusion criteria
Exclusion criteria: Exclusion criteria for healthy subjects: 1. Had taken gastrointestinal motility enhancer, respiratory system inhibitor, neurostimulant, muscle relaxant, etc., within 1 month before enrollment; 2. Pregnant women, lactating women or menstruating women; 3. Have a history of brain trauma, head and neck radiation or oral surgery, neuromuscular diseases resulting in impaired swallowing function; 4. the body is implanted or left with metal objects, the installation of electronic devices such as cardiac pacemaker, unstable condition cannot cooperate with the examination of patients; 5. Severe claustrophobia. Exclusion criteria for patients with dysphagia after stroke: 1. Non-unilateral hemispheric stroke; 2. Previous history of stroke or brain tumor, brain trauma and other neurological, psychiatric history, and history of head and neck radiation or oral surgery; 3. Previous history of dysphagia;combined with cognitive dysfunction, aphasia; 4. Serious diseases of the heart, lungs, liver, pancreas, kidney and other organs;metal objects are implanted or left in the body, electronic devices such as pacemakers are installed, and patients with unstable conditions cannot cooperate in the examination; 5. those with severe visual impairment; 6. can not cooperate with the examination and treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Oral delivery time;Soft palate lift time;Hyoid displacement time;Vestibular closure time;Opening time of the cricopharyngeal muscle;The forward displacement distance of the hyoid bone;The distance of upward displacement of the hyoid bone;Opening amplitude of the cricopharyngeal muscle;Pharyngeal contraction rate;Duration of pharyngeal pressure;Pharyngeal pressure rise rate;UES resting pressure;UES relaxation duration;Peak pharyngeal pressure;UES residual pressure;Peak pressure before UES opening;Peak pressure after UES opening;motor evoked potential;brain region activation;functional connectivity; | — |
Countries
China
Contacts
Public ContactLin Tuo
The Second Affiliated Hospital of South China University of Technology /Guangzhou First People's Hospital
Outcome results
None listed