colorectal cancer
Conditions
Interventions
Sponsors
Shuguang Hospital, Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Patients who are diagnosed as colorectal cancer by pathology, cytology or imaging, and whose histological type is carcinoma, mucinous adenocarcinoma, signet ring cell carcinoma; 2. Colorectal cancer patients with stage IV according to AJCC staging; 3. RAS, BRAF wild-type, advanced unresectable colorectal cancer patients receiving chemotherapy combined with cetuximab; 4. After PET-CT, CT, MRI, bone scan and other imaging examinations, there is at least one measurable lesion; 5. TCM syndrome differentiation belongs to the syndrome of liver fire offending the stomach; 6. 18 years old = 60 points; 8. Estimated survival time >= 3 months; 9. Blood routine, liver function, kidney function, and heart function are generally normal, in line with chemotherapy indications; 10. Have good compliance and sign informed consent to cooperate with this research.
Exclusion criteria
Exclusion criteria: 1. Combined with other primary tumors; 2. Patients with severe cardiovascular and cerebrovascular diseases or severe mental illness; 3. Those who have used chemotherapy or Chinese medicine for less than 2 cycles; 4. Patients with active tuberculosis or infection; 5. Those who are unable to take drugs orally; 6. Those who have poor compliance and cannot complete the research; 7. Those who have participated in other clinical trials in the past month. 8. Women during pregnancy or breastfeeding.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| progression free survival; | — |
Secondary
| Measure | Time frame |
|---|---|
| overall survival;Quality of Life; | — |
Countries
China
Contacts
Public ContactWang Yan
Outcome results
None listed