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A randomized, double-blind, parallel controlled, phase II clinical trial of reconstructing central nerve loop with Visual Auditory tactile multisensor stimulation in the treatment of hand sensory dysfunction after peripheral nerve injury

A randomized, double-blind, parallel controlled, phase II clinical trial of reconstructing central nerve loop with Visual Auditory tactile multisensor stimulation in the treatment of hand sensory dysfunction after peripheral nerve injury

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000036684
Enrollment
Unknown
Registered
2020-08-24
Start date
2020-10-01
Completion date
Unknown
Last updated
2020-09-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Peripheral Nerve Injury

Interventions

Multi sensory stimulation rehabilitation group:Multi sensory stimulation
Regular rehabilitation group:Regular rehabilitation

Sponsors

Yueyang Hospital of Intergrated Tradiontal Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Patients with sensory and motor dysfunction of hand caused by severe peripheral nerve injury of one upper limb; 2. More than 1 year after the first injury and nerve repair surgery; 3. Over 18 years old, male or female; 4. According to the simple mental state examination table, the mental state is normal and can execute the treatment instruction; 5. Be able to tolerate the dosage of 30 minutes per day; 6. Those who voluntarily participated in the study and signed the informed consent form; 7. No relevant rehabilitation training.

Exclusion criteria

Exclusion criteria: 1. Other bone and joint diseases or injuries of upper limbs (such as joint fixation contracture, frozen shoulder, severe arthritis, fracture, etc.); 2. Patients with serious life-threatening primary diseases (such as chronic heart failure, chronic pulmonary failure, renal failure, etc.) and mental diseases (such as depression and cognitive dysfunction); 3. Those who cannot receive treatment and regular follow-up in designated hospitals for a long time

Design outcomes

Primary

MeasureTime frame
Tactile threshold;

Secondary

MeasureTime frame
Two point discrimination;Disabilities of the arm shoulder and hand,DASH;Functional magnetic reosonance imaging;Transcrainial Magnetic Stimluation- Motor Cortex Evoke Potential;

Countries

China

Contacts

Public ContactXu-Yun Hua

Yueyang Hospital of Intergrated Tradiontal Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine

swrhxy@126.com+86 13564020161

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026