Focal liver disease
Conditions
Interventions
Gold Standard:Pathologic diagnosis
Index test:Sonazoid 
contrast-enhanced 
ultrasound 
imaging
Sponsors
Zhongshan Hospital, Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Chinese citizens, >= 18 years old and <= 85 years old; 2. Routine ultrasound indicates that the liver has a clear focus, with liver parenchyma around it, and pathological tissue results can be obtained from the focus and liver parenchyma; 3. Contrast-enhanced ultrasound (showing Zhuoan) examination is possible, and there is an enhanced MRI examination result. If an enhanced MRI examination is not possible, an enhanced CT examination result should be available; for patients with liver fibrosis after hepatitis, the liver parenchymal elastography examination result can be added; 4. If the subject is a female, it should be a non-pregnant or lactating female; 5. The patient voluntarily joined the study and signed an informed consent form.
Exclusion criteria
Exclusion criteria: 1. The subject is known to be allergic to perfluorobutane gas or any component of Sonazoid; 2. The researcher believes that the subject is not suitable for participating in this research.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| imaging features of grayscale Ultrasound;imaging features of Sonazoid CEUS;imaging features of SWE and SWD;SEN, SPE, ACC, AUC of ROC; | — |
Countries
China
Contacts
Public ContactDong Yi
Department of Ultrasound, Zhongshan Hospital, Fudan University
Outcome results
None listed