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A prospective, randomized controlled study on the prevention of calcium oxalate stone by adjusting intestinal flora with high dietary fiber diet

A prospective, randomized controlled study on the prevention of calcium oxalate stone by adjusting intestinal flora with high dietary fiber diet

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000036643
Enrollment
Unknown
Registered
2020-08-24
Start date
2020-09-01
Completion date
Unknown
Last updated
2020-09-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Urolithiasis

Interventions

control group:American guidelines for the Treatment of urolithiasis with drugs provide dietary guidance
experimental group:Commercial fiber packs

Sponsors

Shanghai General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: (Both meet the following criteria) (1) Male urinary calculi patients who underwent surgical removal of calculi; (2) Between the ages of 18 and 60 years; (3) The calculi component analysis results were calcium oxalate; (4) Agree to adhere to the prescribed diet for at least 3 years after obtaining detailed information about the risk factors for urinary calculi.

Exclusion criteria

Exclusion criteria: (Meet any of the following criteria) (1) Patients with common diseases associated with calcium-containing stones (e.g., primary hyperparathyroidism, primary hyperoxaluria, bowel resection, inflammatory bowel disease, tubular acidosis, sponge kidney, etc.); (2) Urological imaging examination (KUB or plain CT) indicated that the calculi were not completely cleared.

Design outcomes

Primary

MeasureTime frame
Recurrence rate of calculi;The composition of Intestinal oxalate degrading bacteria;

Secondary

MeasureTime frame
24h Urine Metabolism Assessment;Imaging of Urinary System;

Countries

China

Contacts

Public ContactYi Shao

Shanghai General Hospital

drshaoyi@163.com+86 13661633372

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026